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Lower Back Pain afflicts an estimated 10 million people annually in the US. Over 700,000 procedures are performed each year to treat Degenerative Disc Disease. Aging baby boomers may double those numbers in the next two decades. The current global spine market is estimated at $7.8B and projected to grow to $21B by 2015.

Back pain is strongly associated with degeneration of the intervertebral disc. Disc degeneration, although in many cases asymptomatic, is also associated with sciatica and disc herniation or prolapse. It alters disc height and the mechanics of the rest of the spinal column, adversely affecting the behavior of other spinal structures such as muscles and ligaments. In the long term, it can lead to spinal stenosis, a major cause of pain and disability in the elderly. Degenerated disc incidence is rising with current demographic changes and an increased aged population.

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